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Contraindications:

– Hypersensitivity to the active substance or to any of the excipients.
– Acute or postoperative pain, since dosage titration is not possible during short-term use.
– Severe impairment of the central nervous system.

Initial Dosing:

Buy fentanyl 75 mcg transdermal should be prescribed only by healthcare professionals who
are knowledgeable in the use of potent opioids for the management of chronic pain.

Application and Handling Instructions:

• Patients should apply Buy fentanyl 75 mcg transdermal to intact, non-irritated, and
non-irradiated skin on a flat surface such as the chest, back, flank, or upper arm. In
young children and persons with cognitive impairment, adhesion should be
monitored and the upper back is the preferred location to minimize the potential of
inappropriate patch removal. Hair at the application site may be clipped (not
shaved) prior to system application.

Avoidance of Heat:

Instruct patients to avoid exposing the Buy fentanyl 75 mcg transdermal application site and
surrounding area to direct external heat sources, such as heating pads or electric
blankets, heat or tanning lamps, sunbathing, hot baths, saunas, hot tubs, and heated
water beds, while wearing the system.

Disposal Instructions:

Failure to properly dispose of Buy fentanyl 75 mcg transdermal has resulted in accidental
exposures and deaths .

Patients should dispose of used patches immediately upon removal by folding the
adhesive side of the patch to itself, then flushing down the toilet.

Unused patches should be removed from their pouches, the protective liners removed,
the patches folded so that the adhesive side of the patch adheres to itself, and
immediately flushed down the toilet.
Patients should dispose of any patches remaining from a prescription as soon as they are
no longer needed.

Addiction, Abuse, and Misuse:

Buy fentanyl 75 mcg transdermal contains fentanyl, an opioid agonist and a Schedule II
controlled substance. As an opioid, fentanyl transdermal system exposes users to the
risks of addiction, abuse, and misuse . As
modified-release products such as fentanyl transdermal system deliver the opioid over an
extended period of time, there is a greater risk for overdose and death due to the larger
amount of fentanyl present.

Neonatal Opioid Withdrawal Syndrome:

Prolonged use of Buy fentanyl 75 mcg transdermal during pregnancy can result in withdrawal
signs in the neonate. Neonatal opioid withdrawal syndrome, unlike opioid withdrawal
syndrome in adults, may be life-threatening if not recognized and treated, and requires
management according to protocols developed by neonatology experts.

Use in Pancreatic/Biliary Tract Disease:

Buy fentanyl 75 mcg transdermal may cause spasm of the sphincter of Oddi. Monitor patients
with biliary tract disease, including acute pancreatitis for worsened symptoms. Buy fentanyl 75 mcg transdermal may cause increases in the serum amylase concentration.

Driving and Operating Machinery:

Strong opioid analgesics impair the mental or physical abilities required for the
performance of potentially dangerous tasks, such as driving a car or operating machinery.
Warn patients not to drive or operate dangerous machinery unless they are tolerant to the
effects of the fentanyl transdermal system.

Pediatric Use:

The safety of Buy fentanyl 75 mcg transdermal was evaluated in three open-label trials in
289 pediatric patients with chronic pain, 2 years of age through 18 years of age. Starting
doses of 25 mcg/hr and higher were used by 181 patients who had been on prior daily
opioid doses of at least 45 mg/day of oral morphine or an equianalgesic dose of another
opioid. Initiation of fentanyl transdermal system therapy in pediatric patients taking less
than 60 mg/day of oral morphine or an equianalgesic dose of another opioid has not been
evaluated in controlled clinical trials.

 

 

 

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